✦ LIBER ✦

Light Activates Reduction of Methotrexate by NADPH in the Ternary Complex with Escherichia coli Dihydrofolate Reductase

✍ Scribed by Yong Qing Chen; Miriam Gulotta; H. T. Andrew Cheung; Robert Callender

Book ID: 111412623
Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 939 KB
Volume: 69
Category: Article
ISSN: 0031-8655
DOI: 10.1111/j.1751-1097.1999.tb05309.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

PHOTOSENSITIZED REDUCTION OF L-BIOPTERIN

PHOTOSENSITIZED REDUCTION OF L-BIOPTERIN IN THE ACTIVE TERNARY COMPLEX OF DIHYDROFOLATE REDUCTASE

✍ John W. Ledbetter Jr.; Wolfgang Pfleiderer; James H. Freisheim 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 986 KB

31P-NMR Studies of NADPH, NADP+ and the

31P-NMR Studies of NADPH, NADP+ and the Complex of NADPH and Methotrexate with Lactobacillus casei Dihydrofolate Reductase in the Solid State

✍ Ioannis P. Gerothanassis; Patrick J. Barrie; Berry Birdsall; James Feeney 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 787 KB

15N NMR studies of the conformation of E

15N NMR studies of the conformation of E. coli dihydrofolate reductase in complex with folate or methotrexate

✍ Fu-Yung Huang; Qing-Xian Yang; Tai-huang Huang 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 394 KB

Sequence-specific1H,13C and15N assignmen

Sequence-specific1H,13C and15N assignment of the TMP-resistant dihydrofolate reductase mutant DHFR(F98Y) in the ternary complex with TMP and NADPH

✍ Serge Altmann; Alexander M. Labhardt; Hans Senn; Kurt Wüthrich 📂 Article 📅 1997 🏛 Springer Netherlands 🌐 English ⚖ 71 KB

Inhibitory properties and X-ray crystall

Inhibitory properties and X-ray crystallographic study of the binding of AR-101, AR-102 and iclaprim in ternary complexes with NADPH and dihydrofolate reductase from Staphylococcus aureus

✍ Oefner, Christian ;Parisi, Sandro ;Schulz, Henk ;Lociuro, Sergio ;Dale, Glenn E. 📂 Article 📅 2009 🏛 International Union of Crystallography 🌐 English ⚖ 898 KB

Iclaprim is a novel dihydrofolate reductase (DHFR) inhibitor belonging to the 2,4-diaminopyrimidine class of antibiotics, of which trimethoprim (TMP) is the most well known representative. Iclaprim exhibits potent bactericidal activity against major Gram-positive pathogens, notably methicillin-sensi

Development of a simple and rapid assay

Development of a simple and rapid assay for the evaluation of inhibitors of human 17α-hydroxylase-C17,20-lyase (P450cl7) by coexpression of P450cl7 with NADPH-cytochrome-P450-reductase in Escherichia coli

✍ Peter B. Ehmer; Joachim Jose; Rolf W. Hartmann 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 113 KB