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Ligation of the α2M Signalling Receptor Elevates the Levels of p21Ras-GTP in Macrophages

✍ Scribed by Uma Kant Misra; Salvatore Vincent Pizzo

Book ID
114284113
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
200 KB
Volume
10
Category
Article
ISSN
0898-6568

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The binding of receptor-recognized forms of a2-macroglobulin (a2M) to macrophage a2M signaling receptors increases inositol-I ,4,5-triphosphate synthesis and induces Ca2+ mobilization. In this report, we demonstrate that ligation of the macrophage a2M signaling receptor is also associated with synth