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Ligaria cuneifolia flavonoid fractions modulate cell growth of normal lymphocytes and tumor cells as well as multidrug resistant cells

✍ Scribed by Paula Cerdá Zolezzi; Teresa Fernández; Paula Aulicino; Victoria Cavaliere; Sofía Greczanik; Eloisi Caldas Lopes; Marcelo Wagner; Rafael Ricco; Alberto Gurni; Silvia Hajos; Elida Álvarez

Book ID: 116569048
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 647 KB
Volume: 209
Category: Article
ISSN: 0171-2985
DOI: 10.1016/j.imbio.2005.03.001

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## Abstract Simultaneous occurrence of resistance to many chemothera‐peutic agents, termed multidrug resistance (MDR), is a complex phenotype. MDR occurs due to several reasons, including over‐expression of a 170‐kDa membrane‐bound protein, called P‐glycoprotein (__P__‐gp), which apparently partici