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Ligand-Targeted Delivery of Therapeutic siRNA

โœ Scribed by Yutaka Ikeda; Kazunari Taira


Book ID
106492816
Publisher
Springer US
Year
2006
Tongue
English
Weight
557 KB
Volume
23
Category
Article
ISSN
0724-8741

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Gene therapy is a promising tool for the treatment of human diseases that cannot be cured by rational therapies. The major limitation for the use of small interfering RNA (siRNA), both in vitro and in vivo, is the inability of naked siRNA to passively diffuse through cellular membranes due to the st