We examine the ligand requirements for the divinylsulphone (DVS) based T-gel to bind immunoglobulins. The original gel consisted of 2-mercaptoethanol coupled to a DVS activated support, with both the thioether and sulphone sulphurs thought necessary for protein binding. No differences in the capacit
β¦ LIBER β¦
Ligand structure of the divinylsulfone-based T-gel
β Scribed by Judith A. Scoble; Robert K. Scopes
- Book ID
- 108341174
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 600 KB
- Volume
- 787
- Category
- Article
- ISSN
- 1873-3778
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## Abstract PβGlycoprotein (Pβgp), a transmembrane, ATPβdependent drug efflux transporter, has attracted considerable interest both with respect to its role in tumour cell multidrug resistance and in absorptionβdistribution and elimination of drugs. Although known since more than 30 years, the unde