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Ligand recognition by antigen-presenting cell C-type lectin receptors

✍ Scribed by Eamon P McGreal; Joanna L Miller; Siamon Gordon

Book ID
108099487
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
389 KB
Volume
17
Category
Article
ISSN
0952-7915

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## Abstract Dendritic cells (DC) that express the type II C‐type lectin DC‐SIGN (CD209) are located in the submucosa of tissues, where they mediate HIV‐1 entry. Interestingly, the pathogen __Candida albicans,__the major cause of hospital‐acquired fungal infections, penetrates at similar submucosal