Ligand promoted palladium-catalyzed homo-coupling of arylboronic acids
β Scribed by Man Shing Wong; Xiao Ling Zhang
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 51 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
An electrochemical method for generating cationic palladium complexes was integrated into an electrooxidative homo-coupling of arylboronic acids. In the presence of a catalytic amount of TEMPO, the homocoupling reaction proceeded efficiently under argon to afford symmetric biaryls.
In the presence of p-toluenesulfonyl chloride, ligandless palladium chloride catalyzes the homo-coupling of arylboronic acids to afford symmetrical biaryls in excellent yields.
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## Abstract A series of solvents were examined for the ligand free Pd(II)βcatalyzed Suzuki reaction of 4βbromotoluene with phenylboronic acid. It was found that the PdCl~2~/__i__βPrOH system could efficiently inhibit the homoβcoupling of phenylboronic acid and give a crossβcoupling product in high