๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Ligand interaction of substituted pyridines with cytochrome P-450

โœ Scribed by Jerry L. Born; Sherrel Early


Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
267 KB
Volume
69
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Studies on the interaction of furan with
โœ Parmar, Devendra ;Burka, Leo T. ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 869 KB

In vitro incubation of rat liver microsomes with ['4C]-furan in the presence of NADPH resulted in the covalent incorporation of furan-derived radioactivity in microsomal protein. Compared to microsomes from untreated rats a two-to threefold increase in binding was observed with microsomes from pheno

Toxic alkaloids and their interaction wi
โœ A. Peeples; R. R. Dalvi ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 304 KB

## Abstract Studies on the binding spectra of certain alkaloids with rat liver microsomes revealed that brucine, scopolamine and strychnine are type I compounds, whereas boldine, emetine, nicotine, reserpine and sanguinarine show type II binding. In contrast, colchicine and solanine failed to produ

Clinical implications of dose-dependent
โœ C. L. DeVane ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 123 KB

The magnitude of drugยฑdrug interactions in vitro involving competitive inhibition of cytochrome (CYP) isozymes by newer antidepressants can theoretically be shown to be dependent upon several factors. These include the concentration of both the substrate and inhibitor, the anity of the inhibitor for