Ligand-free palladium catalysis of aryl coupling reactions facilitated by grinding

✍ Scribed by Liane M. Klingensmith; Nicholas E. Leadbeater

• Book ID: 104252738
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 157 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)02645-x

✦ Synopsis

Ligand-free palladium-catalysed Suzuki coupling reactions and homo-couplings of boronic acids have been facilitated by grinding. The reactions are rapid (10-30 min) and can be performed without the need to exclude air and moisture.