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Ligand coupling through σ-sulfurane — complete retention of configuration of 1-phenylethyl group in the reaction of 1-phenylethyl 2-pyridyl sulfoxide with grignard reagent1

✍ Scribed by Shigeru Oae; Tsutomu Kawai; Naomichi Furukawa


Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
226 KB
Volume
25
Category
Article
ISSN
0040-4039

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Retention stereochemistry in ligand coup
✍ Jun'ichi Uenishi; Atsumi Yamamoto; Takashi Takeda; Shoji Wakabayashi; Shigeru Oa 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 520 KB

## Reactions of-( + )--(I R)-phenybthyl 2-quinolyl (R)- sulfbxide 7a and ( --)-(I R)-phenylethyl2-quinolyl (S)sulfbxide 7b with methylmagnesium bromide were examined. The reaction gave (R)-Z-(Z-phenyle-thy1)quinoline 9 as a ligand-coupling product, and a mixture of methyl(1R)-phenylethyl (R)and (S