The effects of 2-(4-(4-(2-pyrimidinyl)-l-piperazinyl)-butyl)-1,2-benzoisothiazol-3(2H)one-1,1-dioxide hydrochloride (isapirone, TVX Q 7821), a putative 5-HT1 receptor antagonist, has been studied on various models of 5-HT receptor sub-type function. In mice TVX Q 7821 produced a dose-dependent inhib
β¦ LIBER β¦
Ligand Conformation Has a Definitive Effect on 5-HT1A and Serotonin Reuptake Affinity.
β Scribed by Kenneth M. Boy; Michael Dee; Joseph Yevich; John Torrente; Qi Gao; Lawrence Iben; Arlene Stark; Ronald J. Mattson
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 34 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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