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Ligand-Catalyzed Asymmetric Alkynylboration of Enones: A New Paradigm for Asymmetric Synthesis Using Organoboranes

โœ Scribed by Wu, T. Robert; Chong, J. Michael


Book ID
127194760
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
49 KB
Volume
127
Category
Article
ISSN
0002-7863

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The copper catalyzed conjugate addition of n-butyl Grignard to enones in the presence of chiral ferrocenyl phosphine oxazoline ligands has been studied and found to provide useful levels of asymmetric induction. A comparison of the ferrocene derived ligands 3 and 6 with the corresponding phenyl deri