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Ligand Binding Energy and Catalytic Efficiency from Improved Packing within Receptors and Enzymes

✍ Scribed by Dudley H Williams; Elaine Stephens; Min Zhou


Book ID
117143332
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
395 KB
Volume
329
Category
Article
ISSN
0022-2836

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## Abstract The heme‐thiolate protein chloroperoxidase (CPO) catalyzes the chlorination of activated Cο£ΏH bonds. A reaction mechanism is proposed for this enzymatic transformation (__Scheme 1__), and a new iron(III) porphyrinate complex 13 is synthesized containing pentafluorophenyl groups at two __