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Ligand binding and nuclear receptor evolution

โœ Scribed by Hector Escriva; Franck Delaunay; Vincent Laudet


Book ID
101362555
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
225 KB
Volume
22
Category
Article
ISSN
0265-9247

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## Abstract A structureโ€based comparison of the ligandโ€binding domains of 35 nuclear receptors from five different subfamilies is presented. Their ligand and coactivator binding sites are characterized using knowledgeโ€based contact preference fields for hydrophobic and hydrophilic interactions impl