Generation of Affibody® ligands binding
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Caroline Grönwall; Eveline Snelders; Anna Jarelöv Palm; Fredrik Eriksson; Nina H
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Article
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2008
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Portland Press
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English
⚖ 548 KB
Affibody® molecules specific for human IL‐2Rα, the IL‐2 (interleukin‐2) receptor α subunit, also known as CD25, were selected by phage‐display technology from a combinatorial protein library based on the 58‐residue Protein A‐derived Z domain. The IL‐2R system plays a major role in T‐cell activation