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Life without RNase P

✍ Scribed by Randau, Lennart; Schröder, Imke; Söll, Dieter

Book ID: 109897354
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 861 KB
Volume: 453
Category: Article
ISSN: 0028-0836
DOI: 10.1038/nature06833

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## Abstract Metal(II)‐induced hydrolysis of RNA produce products with 5′‐hydroxyls and 2′;3′‐cyclic phosphates at the ends. Ribozymes are RNA molecules that act as catalysts. Some ribozymes that cleave RNA also generate 5′‐hydroxyls and 2′;3′‐cyclic phosphates whereas others produces 5′‐phosphates