Life-threatening thrombotic thrombocytopenic purpura (TTP) in a patient with sickle cell-hemoglobin C disease
β Scribed by H.E. Lee; V.J. Marder; L.J. Logan; S. Friedman; B.J. Miller
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 131 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0939-5555
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We present a case of a patient who developed all manifestations of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) acutely following treatment of cutaneous T-cell lymphoma (CTCL, Sezary syndrome) with deoxycoformycin (pentostatin). Symptoms and signs included severe thrombocy
## Abstract Decreased von Willebrand factor (VWF)βcleaving protease activity (<5%) has been implicated in patients with congenital thrombotic thrombocytopenic purpuraβhemolytic uremic syndrome (UpshawβSchulman syndrome) and associated with mutations within the __ADAMTS13__ gene. In this report, we