Inhibition of cell death by lens-specifi
โ
Fromm, Larry ;Overbeek, Paul A.
๐
Article
๐
1997
๐
John Wiley and Sons
๐
English
โ 367 KB
๐ 1 views
Previous studies on cell cycle regulation in the ocular lens using transgenic mice have shown that inactivation of the retinoblastoma tumor suppressor protein (pRb) can cause postmitotic lens fiber cells to enter the cell cycle. However, when the p53 gene and protein are intact, inactivation of pRb