✦ LIBER ✦

Life and death in mammalian cell culture: strategies for apoptosis inhibition

✍ Scribed by Nilou Arden; Michael J Betenbaugh

Book ID: 113931737
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 253 KB
Volume: 22
Category: Article
ISSN: 0167-7799
DOI: 10.1016/j.tibtech.2004.02.004

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inhibiting the apoptosis pathway using M

Inhibiting the apoptosis pathway using MDM2 in mammalian cell cultures

✍ Nilou Arden; Brian S. Majors; Shin-hyung Ahn; George Oyler; Michael J. Betenbaug 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 634 KB

## Abstract The ability to regulate apoptosis in mammalian cell cultures represents one approach to developing more economical and efficient processes. Genetic modification of cells using anti‐apoptotic genes is one method that may be used to improve cellular performance. This study investigates a

Combining caspase and mitochondrial dysf

Combining caspase and mitochondrial dysfunction inhibitors of apoptosis to limit cell death in mammalian cell cultures

✍ Tina M. Sauerwald; Bruno Figueroa Jr.; J. Marie Hardwick; George A. Oyler; Micha 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 229 KB 👁 1 views

Apoptosis is now recognized as a significant problem in mammalian cell culture. Therefore, in this study, a single gene and multigene approach to inhibit apoptosis has been examined. Stable Chinese hamster ovary (CHO) cell lines were generated to overexpress different single, dual, and triple combin

Inhibiting apoptosis in mammalian cell c

Inhibiting apoptosis in mammalian cell culture using the caspase inhibitor XIAP and deletion mutants

✍ Tina M. Sauerwald; Michael J. Betenbaugh; George A. Oyler 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 293 KB 👁 1 views

Frontiers in Mammalian Cell Culture

✍ Wallace L. McKeehan, David Barnes, Lola Reid, Eric Stanbridge, Hiroki Murakami a 📂 Article 📅 1990 🏛 Society for In Vitro Biology 🌐 English ⚖ 660 KB

Using the Microcyte Flow Cytometer To Mo

Using the Microcyte Flow Cytometer To Monitor Cell Number, Viability, and Apoptosis in Mammalian Cell Culture

✍ Claire L. Harding; David R. Lloyd; Caroline M. McFarlane; Mohamed Al-Rubeai 📂 Article 📅 2000 🏛 American Institute of Chemical Engineers 🌐 English ⚖ 53 KB

Strategies for maximizing metallothionei

Strategies for maximizing metallothionein promoter regulated recombinant protein production in mammalian cell cultures

✍ E. Jervis; D. G. Kilburn 📂 Article 📅 1996 🏛 Springer 🌐 English ⚖ 560 KB

A stably transformed BHK cell line, engineered to produce a human transferrin half-molecule under the control of a mouse metallothionein (MT) promoter, was used as a model system to develop strategies to increase inducible recombinant protein production. Gene expression regulated by the MT promoter