Lidocaine toxicity following subcutaneous administration

✍ Scribed by Salvatore N Alfano; Michael J Leicht; John J Skiendzielewski

• Book ID: 104312668
• Publisher: Elsevier Science
• Year: 1984
• Tongue: English
• Weight: 553 KB
• Volume: 13
• Category: Article
• ISSN: 1097-6760
• DOI: 10.1016/s0196-0644(84)80015-3

✦ Synopsis

Lidocaine Toxicity Following Subcutaneous Administration

A case of a 2-year-old girl who survived grand real seizures secondary to toxicity from massive subcutaneous administration of lidocaine is presented. She was treated with intravenous diazepam and was intubated. After 24 hours of observation she was discharged, and there have been no sequelae or recurrence of seizure activity during ten months follow up. Central nervous system, cardiac, and hematologic effects of Iidocaine toxicity are discussed. Drug interactions that may potentiate lidocaine toxicity are listed.