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Lidocaine attenuates muscarinic receptor-mediated inhibition of adenylyl cyclase in airway smooth muscle

โœ Scribed by Motonari Yunoki; Tsutomu Nakahara; Akiko Mitani; Takeshi Maruko; Yuko Kubota; Kenji Sakamoto; Kunio Ishii

Book ID
114015667
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
174 KB
Volume
470
Category
Article
ISSN
0014-2999

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The muscarinic receptor subtype involved in human airway smooth muscle contraction was characterised for the first time, using subtype-selective muscarinic antagonists. It was demonstrated that methacholine-induced contraction of central (trachea) and peripheral (small bronchi) airway smooth muscle