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LH-RH antagonists: design and synthesis of a novel series of peptidomimetics

โœ Scribed by De, Biswanath; Plattner, Jacob J.; Bush, Eugene N.; Jae, Hwan Soo; Diaz, Gilbert; Johnson, Edwin S.; Perun, Thomas J.

Book ID
126013584
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
372 KB
Volume
32
Category
Article
ISSN
0022-2623

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Opiate antagonists stimulate the release of LH and might, therefore, contribute to an innovative therapy for the treatment of numerous clinical syndromes characterized by hypofnnction of the HHG axis. The purpose of this work was to design and synthesize pure opiate antagonists useful for this thera