Lewis Base Catalyzed Trifluoromethylation of Aldimines with (Trifluoromethyl)trimethylsilane.
β Scribed by Yoshikazu Kawano; Hidehiko Fujisawa; Teruaki Mukaiyama
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 19 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Previously difficult to prepare, aliphatic and alicyclic trifluoromethylketones (e.g. 1 and 2), which are of pharmacalogic interest as potential enzyme inhibitors, can now be synthesized easily and efficiently. The one-step reaction starting with carbonic esters and trimethyl(trifluoromethyl)silane
Cesium Fluoride Catalyzed Trifluoromethylation of Esters, Aldehydes, and Ketones with (Trifluoromethyl)trimethylsilane. -The title reaction is successfully applied to carboxylic, sulfonic, sulfinic, and selenic esters, and also to aldehydes and ketones, among them substrates that have been reported