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Lewis Base-Catalyzed Additions of Alkynes Using Trialkoxysilylalkynes

✍ Scribed by Lettan, Robert B.; Scheidt, Karl A.


Book ID
120928936
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
107 KB
Volume
7
Category
Article
ISSN
1523-7060

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Room Temperature Lewis Base-Catalyzed Al
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## Abstract An efficient and mild access to mixed dimethylalkynylaluminum reagents has been developed __via__ a direct Lewis base‐catalyzed alumination of terminal alkynes by trimethylaluminum. The use of bis(trimethylsilyl)methylamine enables the metalation at room temperature with only 1% of cata