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Lewis acids, especially zinc chloride: A new type of carbodiimide additive in peptide synthesis

✍ Scribed by H.-D. Jakubke; Ch. Kleßen; E. Berger; K. Neubert

Book ID
104245638
Publisher
Elsevier Science
Year
1978
Tongue
French
Weight
231 KB
Volume
19
Category
Article
ISSN
0040-4039

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Copper chloride was found to be an extremely efficient additive suppressing racemization in the carbodiimide mediated couplings. The use of additives in the dicyclohexylcarbodiimide (DCC) method is an important improvement contributing to the suppression of racemization in segment couplings. Among a