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Lewis acid promoted conjugate addition of vinylmagnesium bromide to chiral α,β-unsaturated N-acyl oxazolidinones

✍ Scribed by Yinglin Han; Victor J. Hruby

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
185 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

Lewis acid promoted conjugated additions of vinylmagnesium bromide to chiral ot,13unsaturated N-acyl oxazolidinones are described. A series of enatiomerically pure [5-branched 4-pentenoic acid derivatives have been synthesized with high diastereoselectivity.

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