Lewis-acid promoted addition of 2-trimethylsilyloxyfuran to nitrones: Synthesis and absolute configuration of tetrahydro-2-benzyl-3-(1-benzyloxyethyl)-furo[2,3-d]isoxazol-5(2H)ones
โ Scribed by Carlo Castellari; Marco Lombardo; Graziano Pietropaolo; Claudio Trombini
- Book ID
- 108036421
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 516 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0957-4166
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๐ SIMILAR VOLUMES
Cascade assembly of N,N 0 -dialkylbarbituric acids and aldehydes in the presence of bromine leads to the selective and efficient formation of substituted 1,5-dihydro-2H,2 0 H-spiro(furo[2,3-d]pyrimidine-6,5 0pyrimidine)-2,2 0 ,4,4 0 ,6 0 -(1 0 H,3H,3 0 H)-pentones in 70-88% yields via a complex casc
## Abstract Reaction of barbituric acid (I) with aromatic aldehydes is investigated in the presence of bromine under 2 different sets of reaction conditions.
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