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Lewis Acid Mediated α-Thioalkylation of Ketones

✍ Scribed by Reetz, M. T.; Giannis, A.


Book ID
120068238
Publisher
Taylor and Francis Group
Year
1981
Tongue
English
Weight
228 KB
Volume
11
Category
Article
ISSN
0039-7911

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The Lewis acid mediated cyclisation of various methylenecyclopropyl ketones, ketals and aldehydes has been investigated as a new route to six-and seven-membered rings. Cyclisation of aldehyde 6, ketal 9 and ketone 11 with TiCI 4 gave cyclohexene products, and cyclisation of ketal 10 gave a dichloroc