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Lewis Acid-Catalyzed CH Functionalization for Synthesis of Isoindolinones and Isoindolines

✍ Scribed by Bo Qian; Shengmei Guo; Chungu Xia; Hanmin Huang


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
245 KB
Volume
352
Category
Article
ISSN
1615-4150

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Lewis Acid Catalyzed Synthesis of Aziridines. -A convenient synthesis of the title compounds becomes possible in the presence of Lewis acids. The enamines (VI) and (VII), formed as by-products, can be easily removed by SiO2 chromatography. AlCl3 or TiCl4 generally give similar results.