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Levels of soluble endothelium-derived adhesion molecules in patients with sickle cell disease are associated with pulmonary hypertension, organ dysfunction, and mortality

✍ Scribed by Gregory J. Kato; Sabrina Martyr; William C. Blackwelder; James S. Nichols; Wynona A. Coles; Lori A. Hunter; Marie-Luise Brennan; Stanley L. Hazen; Mark T. Gladwin

Book ID: 108673388
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 205 KB
Volume: 130
Category: Article
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.2005.05701.x

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## Abstract Pulmonary hypertension (PH), a risk factor for mortality in sickle cell disease (SCD), has pathologic features of both pulmonary arterial hypertension (PAH) and PH related to left‐sided heart disease (LHD) suggesting a link between these two entities. We hypothesized that both are chara