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Levels of DNA methylation in diploid and SV40 transformed human fibroblasts

โœ Scribed by T. Matsumura; F. Malik; R. Holliday

Book ID
113371072
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
264 KB
Volume
24
Category
Article
ISSN
0531-5565

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Decreased methylation rates of DNA in SV
Decreased methylation rates of DNA in SV40-transformed human fibroblasts
โœ Lee J. Levitt; Gerry R. Boss; Richard W. Erbe ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 550 KB

The rates of methylation of total cellular DNA and newly synthesized DNA were measured in four unrelated SV40-transformed human fibroblast lines and in four control parent fibroblast lines. Rates of methylation of total cellular DNA were decreased by a factor of 1.8-2.3 in the transformed cells rela