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Level A in vivo–in vitro correlation: Nonlinear models and statistical methodology

✍ Scribed by Adrian Dunne; Thomas O'Hara; John Devane

Book ID
109388854
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
132 KB
Volume
86
Category
Article
ISSN
0022-3549

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✍ H. Kortejärvi; J. Malkki; M. Marvola; A. Urtti; M. Yliperttula; P. Pajunen 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 240 KB

In vitro-in vivo correlation (IVIVC) models for formulation series are useful in drug development, but the current models are limited by their inability to include data variability in the predictions. Our goal was to develop a level A IVIVC model that provides predictions with probabilities. The Bay