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Level a in Vitro/in Vivo Correlations: A Quality Control Tool or Bioequivalence Predictor for Extended-Release Solid Oral Dosage Forms?

✍ Scribed by Tandt, Ludo A. G. L.; Stubbs, Christopher; Kanfer, Isadore


Book ID
111646009
Publisher
Informa plc
Year
1995
Tongue
English
Weight
685 KB
Volume
21
Category
Article
ISSN
0363-9045

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Defining a quantitative and reliable relationship between in vitro drug release and in vivo absorption is highly desired for rational development, optimization, and evaluation of controlled-release dosage forms and manufacturing process. During the development of a once-daily extended-release (ER) t