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Levamisole inhibits in vivo rat platelet aggregation by a release of prostacyclin-like factor

โœ Scribed by Pinto, A.; Sorrentino, R.; Sorrentino, L.


Book ID
122693965
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
436 KB
Volume
21
Category
Article
ISSN
0306-3623

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In vitro inhibition of rat platelet aggr
โœ Omar, Rabeea F. ;Randell, Edward ;Rahimtula, Anver D. ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 680 KB

The mycotoxin ochratoxin A (OA) consists of 5-chloro-3-methyl-3,4-dihydro-8-hydroxyisocoumarin moiety linked by an amide bond to p-Lphenylalanine. When added to washed rat platelets in vitro, OA caused a dose-dependent inhibition of aggregation induced by agonists such as adenosine diphosphate (ADP)