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Leukotriene C4 enhances the contraction of porcine tracheal smooth muscle through the activation of Y-27632, a rho kinase inhibitor, sensitive pathway

✍ Scribed by Hidekazu Setoguchi; Junji Nishimura; Katsuya Hirano; Shosuke Takahashi; Hideo Kanaide

Book ID
110005455
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
183 KB
Volume
132
Category
Article
ISSN
0007-1188

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## Abstract ## Aims To investigate the concentration and activity of RhoA in detrusor and urothelium, as well as the effects of a Rho‐kinase inhibitor, Y‐27632 {(+)‐(R)‐trans‐4‐(1‐aminoethyl)‐N‐(4‐pyridyl) cyclohexanecarboxamide dihydrochloride}, on contraction of the pig urinary bladder. ## Meth