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Leukotriene B4metabolism in human leukocytes: Fact or artefact?

✍ Scribed by R. M. McMillan; S. J. Foster; P. A. Dieppe


Publisher
SP Birkhäuser Verlag Basel
Year
1987
Tongue
English
Weight
199 KB
Volume
21
Category
Article
ISSN
1420-908X

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The effects of leukotriene D4 on the intracellular pH of human rnyelocytes, derived from cultured HL-60 cells by dimethylsulfoxide-induced differentiation, were quantified with the fluorescent indicator 2',7'-bis-(2-carboxy-ethyl)-5,6carboxyfluorescein. Leukotriene D4, but not C4 or E4, increased in