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Leukocytoclastic-vasculitic neuropathy associated with chronic Epstein–Barr virus infection

✍ Scribed by Kazuaki Kanai; Satoshi Kuwabara; Masahiro Mori; Kimihito Arai; Takako Yamamoto; Takamichi Hattori

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 128 KB
Volume: 27
Category: Article
ISSN: 0148-639X
DOI: 10.1002/mus.10287

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✦ Synopsis

Abstract

We report a patient with leukocytoclastic‐vasculitic neuropathy associated with chronic Epstein–Barr virus (EBV) infection. A 55‐year‐old man had been suffering from chronic progressive axonal polyneuropathy and skin erythema for 3 years. A skin biopsy showed capillary vasculitis with clustered leukocyte fragments. Findings of serum assays, a polymerase chain reaction for EBV‐DNA, and in situ hybridization indicated chronic EBV infection. Immunosuppressive treatment resulted in the gradual lessening of his general and neurologic symptoms. Muscle Nerve 27:113–116, 2003

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