Communicated by Charles J. Epstein Leukocyte adhesion deficiency (LAD) is an inherited immunodeficiency disorder caused by CD 18 subunit abnormality dependent defective expression of pz integrins on the surface of leukocytes. On analysis of the CD18 molecular defect in a female Japanese patient with
β¦ LIBER β¦
Leukocyte Adhesion Deficiency II: Therapy and Genetic Defect
β Scribed by Wild, Martin K.; Lühn, Kerstin; Marquardt, Thorsten; Vestweber, Dietmar
- Book ID
- 121078594
- Publisher
- S. Karger AG
- Year
- 2002
- Tongue
- English
- Weight
- 436 KB
- Volume
- 172
- Category
- Article
- ISSN
- 1422-6405
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## Heterogeneity in the molecular defect leading to the leukocyte adhesion deficiency* Leukocyte adhesion deficiency (LAD) is a recessive autosomal disease characterized by life-threatening recurrent bacterial infections, by defective functions of leukocytes and by deficient membrane expression of