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Leukemia inhibitory factor: A paracrine mediator of bone metabolism

✍ Scribed by Sims, Natalie A.; Johnson, Rachelle W.

Book ID
120387873
Publisher
Informa plc
Year
2012
Tongue
English
Weight
334 KB
Volume
30
Category
Article
ISSN
0897-7194

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Leukemia inhibitory factoridilferenti at ion-sti mu 1 ati ng factor (LI F/D-factor), expression of its mRNA, and possible roles in bone metabolism were studied in murine primary and clonal osteoblast-like cells. Local bone-resorbing factors such as IL-1, TNFcr, and LPS strongly induced expression of