✦ LIBER ✦

Leukemia in chiladhood: Introduction and etiology

✍ Scribed by John R. Hartmann

Publisher: John Wiley and Sons
Year: 1975
Tongue: English
Weight: 306 KB
Volume: 35
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(197503)35:3+<996::aid-cncr2820350722>3.0.co;2-a

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✦ Synopsis

Striking improvement in the treatment of certain childhood cancers during the past decade has resulted from a combined multidisciplinary approach utilizing surgery, irradiation, and chemotherapy early in the disease process. Early use of long-term combination chemotherapy fsllowing definitive clinical and hematologic staging has resulted in significant "cure" rates in several diseases. The etiology of childhood leukemia remains unknown. Implicated have been viruses, genetic abnormalities leading to increased susceptibility, exposure to various chemicals, and at times obscure hereditary or familial factors. The recurrence of leukemia in donor cells in a leukemic child following bone marrow transplantation is reported for the second time.

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