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Leucovorin rescue of human cancer and bone marrow cells following edatrexate or methotrexate

✍ Scribed by Jacques Jolivet; Gerrit Jansen; Godefridus J. Peters; Marie-France Pinard; Jan H. Schornagel

Book ID
115783838
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
768 KB
Volume
47
Category
Article
ISSN
0006-2952

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✍ Bruce D. Minsky; John Conti; Alfred M. Cohen; David P. Kelsen; Len Saltz; Jose G πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 682 KB

We present an analysis of acute toxicity of 3 cycles of neoadjuvant bolus methotrexate (MTX) with leucovorin (LV) rescue plus bolus 5-FU, followed by continuous infusion 5-FU with concurrent pre-operative 5040 cGy, and post-operative bolus 5-FU/ LV in patients with rectal cancer. Nine patients (1: u