Leucocyte glucose-6-phosphate dehydrogenase (G-6-PD) activity in G-6-PD deficient subjects
β Scribed by F. Tzortzatou-Stathopoulou; L. Zannos-Mariolea; P. Karayiannis; N. Constantsas; N. Matsaniotis
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 229 KB
- Volume
- 135
- Category
- Article
- ISSN
- 0340-6997
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We screened 38 G6PD-deficient male Chinese neonates for known G6PD mutations using established PCR-based techniques. We found 50.0% (19 of 38) were mutation 1376G>T, 34.2% (13 of 38) were mutation 1388G>A, 5.2% (2 of 38 ) were mutation 95A>G and 2.2% (1 of 38) was mutation 1024C>T. In 7% (3 of 38) o
We performed DNA analysis using cord blood samples on 86 male Malay neonates diagnosed as G6PD deficiency in the National University of Malaysia Hospital by a combination of rapid PCR-based techniques, single-stranded conformation polymorphism analysis (SSCP) and DNA sequencing. We found 37.2% were