✦ LIBER ✦

Leucocyte adherence inhibition and carcinoembryonic antigen in combination for diagnosis of colorectal cancer

✍ Scribed by J. E. Payne; O. Dent; P. H. Chapuis; H. J. Meyer; M. A. Sutherland; A. Ruwoldt

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 312 KB
Volume: 22
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930220315

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A combination of leucocyte adherence (LAI) and carcinoembryonic antigen (CEA) diagnosed colorectal carcinoma with 91% sensitivity and 68% specificity. Relative operating characteristic (ROC) analysis was used to calculate the cutoff points for optimum detectability in a group of 159 patients with bowel symptoms who were investigated by endoscopy and radiology. Combining LAI and CEA would be likely to reduce the chance of missed diagnosis of colorectal carcinoma when x‐ray and colonoscopic findings are equivocal.

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