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Leucine inhibits proteolysis by the mTOR kinase signaling pathway in skeletal muscle

✍ Scribed by J.C. Mitchell; A.R. Evenson; N.E. Tawa Jr

Book ID
116701591
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
46 KB
Volume
121
Category
Article
ISSN
0022-4804

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## Abstract Endotoxin (i.e., lipopolysaccharide, LPS) impairs skeletal muscle protein synthesis. Although this impairment is not acutely associated with a decreased plasma concentration of total amino acids, LPS may blunt the anabolic response to amino acids. To examine this hypothesis, rats were i