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Leucine aminopeptidases: diversity in structure and function

✍ Scribed by Matsui, Mikiko (author);Fowler, Jonathan H. (author);Walling, Linda L. (author)


Book ID
118264805
Publisher
Walter de Gruyter GmbH & Co. KG
Year
2006
Tongue
English
Weight
106 KB
Volume
387
Category
Article
ISSN
1431-6730

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Human pregnancy serum and placenta have the ability to degrade uterotonic peptide oxytocin (OT). Placental leucine aminopeptidase (P-LAP), which is also called cystine aminopeptidase, is the only membrane aminopeptidase known to functionally degrade OT as oxytocinase (OTase). P-LAP/OTase hydrolyzes