β Scribed by Bennett, John M.
No coin nor oath required. For personal study only.
Dr. Alsabi (1979) has described 28 adult patients with "acute myelogenous leukemia," all of whom had elevated serum lysozyme levels (98.6-212.4 pg/ml) before treatment. He reports only one patient with "monomyelocytic leukemia" as having the highest serum lysozyme level; namely, 3 18.9 pg/ml.
Virtually all other series distinguish between acute myeloblastic, acute myelomonocytic, and acute monocytic leukemia [eg, 1,2].
It is highly unlikely that all 28 patients had only myeloblastic morphology or no sig nificant percentage of sodium fluoride-inhibited esterase. Approximately 40-50% of such cases are myelomonocytic by standard cytochemical criteria. Moreover, attempts have been made to correlate morphology, lysozyme levels, and cytochemistry with response and survival [3] .
correlation between morphology and lysozyme levels.
π SIMILAR VOLUMES