We report an 8-year-old boy with Ph-positive chronic myelogenous leukemia (CML) who showed a testicular tumor as the first manifestation of blastic crisis. Pathological examination of the excised testis revealed marked infiltration of immature cells, whereas bone marrow remained in the chronic phase
โฆ LIBER โฆ
Letter to the editor: Lymphoid blastic crisis in Ph-negative chronic myeloid leukemia
โ Scribed by Erica Sigler; Alain Berrebi
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 107 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0361-8609
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A 23-year-old man developed Ph'-positive chronic myelogenous leukemia in 1966. After two short courses of busulfan not associated with severe myelosuppression, the frequency of Ph'-positive metaphases in his bone marrow was 40%. Over the next eight years, he remained hematologically stable without f