## Abstract The advent of gene targeting has allowed the dissection of many essential cellular pathways, including those involved in cell cycle regulation, signal transduction, and development. However, it is becoming increasingly clear that the simple gene deletion strategy may not be sufficient f
Lessons learned from art pardee in cell cycle, science, and life
✍ Scribed by Q. Ping Dou
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 152 KB
- Volume
- 209
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
This essay is written to honor Dr Art Pardee's 85th birthday (July 13, 2006). In this essay, I have summarized the lessons I learned from Art and the cell‐cycle research I performed in Art's laboratory during my postdoctoral training period. I have also summarized some research from my own laboratory that has been inspired by the lessons I learned from Art, including the interactions between cell cycle and cell death regulators and discovery of novel polyphenol‐ and copper‐based proteasome inhibitors. Finally, I have discussed the potential use of these proteasome inhibitors in cancer prevention and treatment. J. Cell. Physiol. 209: 663–669, 2006. © 2006 Wiley‐Liss, Inc.
📜 SIMILAR VOLUMES