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Lessons from the design of a novel atomic potential for protein folding

✍ Scribed by William W. Chen; Eugene I. Shakhnovich

Book ID
111752492
Publisher
Cold Spring Harbor Laboratory Press
Year
2005
Tongue
English
Weight
257 KB
Volume
14
Category
Article
ISSN
0961-8368

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The solution to the protein folding problem lies in defining the relative energetic contributions of short-range and long-range interactions. In other words, the tendency of a stretch of amino acids to adopt a final secondary structural fold is context dependent. Our approach to this problem is to a