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Lesions of substantia nigra by kainic acid: Effects on apomorphine-induced stereotyped behaviour

โœ Scribed by Micaela Morelli; Maria Luisa Porceddu; Gaetano Di Chiara

Book ID
118865725
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
658 KB
Volume
191
Category
Article
ISSN
0006-8993

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Apomorphine-induced yawning in rats is a
Apomorphine-induced yawning in rats is abolished by bilateral 6-hydroxydopamine lesions of the substantia nigra
โœ A. J. Stoessl; C. T. Dourish; S. D. Iversen ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Springer ๐ŸŒ English โš– 669 KB

Apomorphine-induced yawning was studied in male rats with bilateral 6-hydroxydopamine lesions of the substantia nigra. Apomorphine 10, 20 and 50 lag/kg SC induced dose-dependent yawning in unoperated controls and animals with sham lesions. In the lesioned animals (in which the mean striatal dopamine